To lose one's self-control; to act irrationally or wildly especially due to strong emotions.

अपना आपा खोना; अत्यधिक भावनात्मक स्थिति के चलते असंयमित या पागलपन से व्यवहार करना।

English Usage: When he heard the bad news, he went off the deep end and started shouting at everyone.

Hindi Usage: जब उसने बुरी खबर सुनी, तो वह पागल हो गया और सभी पर चिल्लाने लगा।

To be extremely scared or terrified to the point of losing one's sanity or composure.

इतना डर जाना कि होश खो बैठना

English Usage: She was frightened out of her mind when she saw the ghost.

Hindi Usage: जब उसने भूत देखा तो वह डर के मारे पागल हो गई।